Penatalaksanaan neuropati optik traumatik dapat diamati, pemberian steroid atau dekompresi. Akson saraf optik dapat rusak baik secara langsung maupun tidak langsung. Tujuan penelitian: neuropati optik traumatik adalah kondisi langka dan berpotensi mengancam penglihatan yang disebabkan oleh trauma mata atau kepala.
There was no significantly difference in conjunctival epithelial metaplasia and cell to cell contact degree in corneal epithelial cells among these glaucoma treatment groups. Conclusion : Timolol maleat 0,5% caused lower goblet cell density after 3 months therapy compare with latanoprost and fixed combination. Conjunctival epithelial metaplasia degree were increased among group of timolol (p=0,008) and fixed combination (p=0,046). There was no significantly difference between 3 groups in conjunctival epithelial metaplasia degree (p=0,706) and cell to cell contact degree in corneal epithelial cells (p=0.66) after 3 months therapy. Goblet cell density in timolol group was lower than latanoprost (p=0,041) and fixed combination (p=0,045). Result : There were differences between 3 groups in goblet cells density after 3 months therapy (p=0,030). All topical antiglaucoma in this study were preservative free. A total of 45 eyes from 31 patients were used as subject and distributed onto three groups treatment, which were timolol maleat 0.5%, latanoprost 0.005%, and latanoprost-timolol maleat fixed combination. Methods : This was a randomized controlled trial study with single blind masking. Objective : This study was to understand ocular surface remodeling due to active substance of topical antiglaucoma with impression cytology examination among the patient prior and 3 months after therapy.
Goblet cell density decrease is the most important parameter on evaluation of ocular surface disorder. Impression cytology examination may reveal superficial epithelial cells on conjunctiva and cornea, including goblet cells. Introduction : The longterm use of topical antiglaucoma might cause ocular surface instability due to active substance or preservative used.
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